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NexGard vs Comfortis

Compare NexGard Chewables to Comfortis Tablets

Oral treatments such as chewables or tablets are a popular and fuss-free way to treat your pet for fleas, avoiding the mess of a topical solution.

NexGard chewables (Afoxolaner) and Comfortis tablets (Spinosad) are both monthly oral treatments that kill adult fleas, breaking the breeding cycle by preventing them from laying eggs. NexGard has the additional benefit of killing ticks.

Comfortis, which is available for both dogs and cats, has a faster acting formula. It starts to kill fleas within 30 minutes of administration, reaching 98% effectiveness within 4 hours.

NexGard is suitable for slightly younger dogs and puppies, from 8 weeks of age and weighing 4 lbs (1.8kg). Comfortis may only be administered to dogs over 14 weeks, weighing 5 lbs (2.3kg) minimum, and cats over 14 weeks, weighing 4.1 lbs (1.9kg) minimum.

Top tip: Fleas and ticks can carry nasty diseases, but protecting your pet doesn’t need to be difficult. Use our comparison chart to weigh up the pros and cons of the most popular products.

  NexGard Comfortis
Kills Fleas yes tick yes tick
Repels Fleas - -
Kills Flea Eggs and Larvae Kills newly emerged fleas before they can lay eggs -
Kills Ticks yes tick -
Repels Ticks - -
Kills and/or Repels Mosquitoes - -
Other Parasites    
Safe for Pregnant or Nursing Pets - Consult your veterinarian first
When does it starts working Kills 100% of fleas within 24 hours Kills fleas in 30 minutes
Application Beef-flavored chewable Beef-flavored tablet
Active Ingredient(s) Afoxolaner Spinosad
Dosage Monthly Monthly

NexGard vs Comfortis

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Nexgard for Dogs 4-10 lbs (2-4kg) 12 Chewables